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Educational Day in 's-Hertogenbosch!

Thursday October 16th 2008 will be the Educational Day of the ESID meeting.

Have a look at the programme at a glance

ESID Juniors Working Party Report, November 2008

This report describes achievements of the ESID Juniors in the last two years and it also outlines our future activities on which we want to focus during the next two years.


ESID Young Researchers Corner-News@ESID Fall 2012, by Sara Ciullini Mannurita

Guidelines for HSCT for autoimmune disorders

Updated conditioning guidelines for HSCT in autoimmune disorders Msword, 26.00 kB...

IgA Deficiency

Definitive Male or female patient greater than 4 years of age who has a serum IgA of less than 7 mg/dl (0.07 g/L) but normal serum IgG and IgM, in whom other causes of hypogammaglobulinemia have been excluded (see 'Differential Diagnosis of Hypogamma...

Leukocyte Adhesion Defects (LAD)

Definitive A male or female patient with decreased intensity of expression of CD18 on neutrophils (less than 5% of normal) and at least one of the following: Mutation in the b2 integrin gene Absence of b2 integrin mRNA in leukocytes Probable...

MHC-Class II Deficiency

Definitive Male or female patient with decreased intensity of expression (less than 5% of normal) of HLA-DR or DP on B cells or monocytes and a mutation in one of the following genes: CIITA, RFX-B, RFX-5 or RFX-AP ProbableMale or female patient wi...

New! Molecular analysis of PIDs

The ESID Genetic Working Party wants to help to connect and support the collaborative clinical, genetic laboratories and research units associated with the ESID society.

Quality Assurance For Pneumococcal Assays in Europe

The European Primary Immunodeficiencies (PIDs) Consensus Conference in Langen (2006) outlined the need for quality assurance for assays to measure specific antibodies to common pathogens and immunization antigens. In order to make a diagnosis of primary antibody failure, it is important to show that a patient is unable to make antibodies to pathogens; this may be demonstrated using either common exposure antigens or those used for immunization. Streptococcus pneumoniae, a common gram positive bacterium, is one such pathogen that is estimated by the WHO to be responsible for over one million acute deaths worldwide. This includes patients with primary immune deficiencies, who are particularly susceptible to infections caused by encapsulated bacteria.

Severe Combined Immunodeficiency (SCID)

Definitive Male or female patient less than 2 years of age with either a) engraftment of transplacentally acquired maternal T cells; or b) less than 20% CD3+ T cells, an absolute lymphocyte count of less than 3000/mm3 and at least one of the followin...